Redefining the experience of cancer through our trusted legacy in nuclear medicine

Pharmaceutical Manufacturing

Nuclear Medicine, PET Imaging, Molecular Imaging, cGMP Manufacturing , Contract Manufacturing, and SPECT Imaging


Paris, France



Curium is the global leader in nuclear medicine, providing life-changing diagnostics and treatment to patients all over the world. We develop, manufacture and distribute world-class radiopharmaceutical products with a renewed focus on cancer, exploring untapped potential for new innovation. We build on remarkable foundations and a legacy of providing reliable and consistent nuclear solutions to tens of thousands of patients every day. Our proven heritage combined with a pioneering approach are the hallmarks from which we provide life-changing diagnostics and therapeutics. Our people are the root of the incredible impact they have. We strive to make the impossible possible and to be an organization that will change the face of medicine. Our diverse group of industry experts is unified under one strong and singular focus – to develop, manufacture and supply revolutionary diagnostic and therapeutic radiopharmaceuticals to our customers around the globe with unrivaled reliability and superior service.
Video - The Curium Way

The Opportunity

Principal Continuous Improvement Engineer

St Louis, MO
  • Overview

    The Principal Continuous Improvement Engineer executes the vision for translating Curium NA’s strategy and goals to efficient, sustainable, and repeatable processes using Six Sigma, Lean and advanced project management techniques. The position creates value by reducing execution time, cost, and errors within the three key operational functions: Development, Manufacturing and Compliance.

  • Responsibilities

    •Designs and implements processes, systems, and governance consistent with Curium’s continuous improvement vision. Collaborates with Development, Manufacturing and Compliance teams to apply continuous improvement principles (Six Sigma, Lean, etc.) to reduce execution time and improve first-time-right performance.

    •Leads ad-hoc expediting efforts, rapid action teams, root cause analysis efforts and Kaizen events to achieve continuous improvement goals. Functions as a supplemental project manager when projects get off-track or face significant barriers. Leverages cross-functional collaboration to achieve timely outcomes from these activities.

    •Partners with Development, Manufacturing and Compliance teams to plan and execute improvement programs. Provides Lean, Six Sigma, data analysis and process design skills to support these programs.

    •Leads data and statistical analysis efforts. Guides teams on leveraging data/statistical outcomes to improve decision making. Reduces execution time and shortens time to detect/resolve critical problems with advanced predictive statistical models and simulations. Shortens new product development time using statistical design of experiments.

    •Administers systems used to support the continuous improvement vision. Develops procedures, reports, and training to facilitate leveraging these systems to efficiently achieve program goals. Develops and manages metrics for monitoring process and system performance.

  • Qualifications

    •Bachelor’s Degree in engineering or related scientific field.

    •10 years of experience in the pharmaceutical industry, with experience as both an individual contributor and as a supervisor/team leader.

    •Assignments in at least two of the following areas: new product development, technical transfer, manufacturing operations, supply chain operations and compliance (FDA, NRC, OSHA, EPA).

    •Trained in Six Sigma and/or Lean; certification as a Six Sigma Black Belt preferred. At least 5 years of demonstrated improvement gains achieved through application of Six Sigma/Lean skills.

    •Excellent critical thinking and problem-solving skills.

    •History of leading high profile problem resolution in high stress/tight timeline situations.

    •Strong business acumen, demonstrating the ability to translate technical process activities to business/financial results.

    •Demonstrated project management experience in estimating, developing, and managing schedules/resource plans.

    •Experience with project management systems and application to multi-stage drug development projects desired.

    •Knowledge of drug manufacturing and related compliance programs (FDA, NRC, EPA, OSHA).

    •Knowledge of radiochemistry, aseptic processes, equipment procurement/construction/qualification and added benefit.

    •Demonstrated skills in leading improvement teams. Skills include team facilitation, process mapping, data collection and analysis, risk assessment, innovation and change implementation.

    •Can create and deliver effective reports and presentations.

    •Skilled in balancing technical and behavioral elements of improvement and change management programs.

    •Works well under pressure; able to function with abstract knowledge and short deadlines.

    •Capable of leading multiple simultaneous projects.


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